[ { "name": "Iwasaki Lab", "pi": "Akiko Iwasaki", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/iwasaki", "raw_description": "The Iwasaki Lab investigates innate and adaptive immune responses to viruses including SARS-CoV-2, herpes simplex virus, and influenza. The lab focuses on sex differences in immunity, mucosal immunology, and mechanisms of antiviral defense.", "tags": ["innate immunity", "antiviral", "COVID-19", "mucosal immunity", "sex differences", "vaccine"], "skills": ["flow cytometry", "mouse models", "viral assays", "single-cell RNA-seq"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Medzhitov Lab", "pi": "Ruslan Medzhitov", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/medzhitov", "raw_description": "Studies the fundamental principles of innate immunity and inflammation, including Toll-like receptor signaling, tissue homeostasis, allergy, and the physiological role of inflammation in organismal health.", "tags": ["innate immunity", "TLR", "inflammation", "allergy", "tissue homeostasis"], "skills": ["mouse models", "cell culture", "biochemistry", "flow cytometry"], "working_style": "wet", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Flavell Lab", "pi": "Richard Flavell", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/flavell", "raw_description": "Uses transgenic and gene-targeted mice to study innate and adaptive immunity, T cell tolerance and activation, and regulation of T cell differentiation. Also studies the microbiome in modulating immune responses and inflammatory disease.", "tags": ["T cell", "immune tolerance", "microbiome", "inflammation", "autoimmunity", "TGF-beta"], "skills": ["mouse models", "flow cytometry", "CRISPR", "genomics"], "working_style": "wet", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Craft Lab", "pi": "Joe Craft", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/craft", "raw_description": "Investigates T follicular helper cells and their role in autoimmune diseases such as lupus. Studies germinal center biology and how dysregulated autoantibody production drives tissue damage in systemic lupus erythematosus.", "tags": ["T follicular helper", "germinal center", "lupus", "autoimmunity", "B cell"], "skills": ["flow cytometry", "mouse models", "ELISA", "confocal microscopy"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Palm Lab", "pi": "Noah Palm", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/palm", "raw_description": "Studies how the microbiome shapes immune development and inflammatory disease. Uses germ-free mouse models and metagenomic approaches to identify microbial regulators of immunity and IBD.", "tags": ["microbiome", "immunity", "inflammation", "germ-free", "gut bacteria", "IBD"], "skills": ["germ-free mouse models", "metagenomics", "flow cytometry", "16S sequencing"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Shlomchik Lab", "pi": "Mark Shlomchik", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/shlomchik", "raw_description": "Examines B cell activation, germinal center biology, and the origins of autoimmunity. Seeks to understand why self-tolerance breaks down in diseases like lupus and rheumatoid arthritis.", "tags": ["B cell", "germinal center", "autoimmunity", "lupus", "self-tolerance"], "skills": ["mouse models", "flow cytometry", "ELISPOT", "immunofluorescence"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Kaech Lab", "pi": "Susan Kaech", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/kaech", "raw_description": "Investigates CD8 T cell differentiation and exhaustion in chronic infection and cancer, with goals of improving immunotherapy and vaccine strategies for persistent viral infections.", "tags": ["CD8 T cell", "T cell exhaustion", "cancer immunotherapy", "chronic infection"], "skills": ["flow cytometry", "mouse models", "single-cell sequencing", "ATAC-seq"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Dhodapkar Lab", "pi": "Madhav Dhodapkar", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/dhodapkar", "raw_description": "Studies tumor immunology and immune responses to cancer, focusing on myeloma, dendritic cell biology, and development of cancer vaccines and immunotherapy strategies.", "tags": ["tumor immunology", "myeloma", "cancer vaccine", "dendritic cells", "immunotherapy"], "skills": ["flow cytometry", "patient samples", "single-cell RNA-seq", "mouse models"], "working_style": "mixed", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Foxman Lab", "pi": "Ellen Foxman", "department": "immunobiology", "contact_email": "ellen.foxman@yale.edu", "lab_url": "https://medicine.yale.edu/lab/foxman", "raw_description": "Studies antiviral defense in the human respiratory tract, focusing on innate immunity and biomarkers of antiviral responses. Uncovered viral interference, in which common cold virus defenses protect against influenza and COVID-19.", "tags": ["antiviral", "respiratory immunity", "innate immunity", "COVID-19", "viral interference"], "skills": ["human airway epithelial cells", "viral assays", "RNA-seq", "flow cytometry"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Herold Lab", "pi": "Kevan Herold", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/herold", "raw_description": "Translational immunology focused on autoimmune Type 1 diabetes. Studies regulation of autoreactive T cells, beta cell protection from immune killing, and conducts clinical trials of novel therapeutics.", "tags": ["Type 1 diabetes", "autoimmunity", "T cell", "beta cell", "clinical trials", "translational"], "skills": ["flow cytometry", "patient samples", "mouse models", "clinical immunology"], "working_style": "mixed", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Lucas Lab", "pi": "Carrie Lucas", "department": "immunobiology", "contact_email": "carrie.lucas@yale.edu", "lab_url": "https://medicine.yale.edu/lab/lucas", "raw_description": "Discovers single-gene defects underlying severe immune disorders in humans and dissects mechanisms revealed by these mutations using patient cells and genetically engineered mouse models.", "tags": ["primary immunodeficiency", "human genetics", "immune dysregulation", "mouse models", "T cell"], "skills": ["CRISPR", "patient samples", "mouse models", "flow cytometry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Lieping Chen Lab", "pi": "Lieping Chen", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/liepingchen", "raw_description": "Focuses on basic T cell biology and translation of discoveries into cancer immunotherapy. Discovered the B7-H1 (PD-L1) molecule and identified the PD-1/PD-L1 pathway as a critical immune evasion mechanism in tumors.", "tags": ["PD-L1", "PD-1", "cancer immunotherapy", "checkpoint blockade", "T cell", "immune evasion"], "skills": ["flow cytometry", "patient samples", "mouse models", "antibody engineering"], "working_style": "mixed", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Dixit Lab", "pi": "Vishwa Deep Dixit", "department": "pathology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/dixit", "raw_description": "Studies immunometabolism and aging. Established the role of NLRP3 inflammasome in inflammaging and immunosenescence. Investigates how caloric restriction and ketogenesis deactivate the inflammasome to improve healthspan.", "tags": ["aging", "immunometabolism", "NLRP3", "inflammasome", "caloric restriction", "healthspan", "longevity"], "skills": ["mouse models", "metabolomics", "flow cytometry", "RNA-seq"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Fikrig Lab", "pi": "Erol Fikrig", "department": "internal medicine", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/fikrig", "raw_description": "Investigates vector-borne diseases including Lyme disease, dengue, West Nile virus, and malaria. Studies immunity to Borrelia burgdorferi and molecular interactions between pathogens, arthropod vectors, and mammalian hosts.", "tags": ["Lyme disease", "vector-borne disease", "flavivirus", "malaria", "tick immunity"], "skills": ["mouse models", "tick biology", "viral assays", "molecular biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Bosenberg Lab", "pi": "Marcus Bosenberg", "department": "dermatology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/bosenberg", "raw_description": "Studies factors that regulate anti-cancer immune responses in melanoma. Has developed widely utilized mouse models to study melanoma formation, progression, and how the immune system can be stimulated to fight cancer.", "tags": ["melanoma", "tumor immunology", "cancer immunotherapy", "mouse models", "skin cancer"], "skills": ["mouse models", "flow cytometry", "IHC", "CRISPR"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Sidi Chen Lab", "pi": "Sidi Chen", "department": "genetics", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/sidichen", "raw_description": "Develops genome editing and high-throughput CRISPR screening technologies for precision cancer modeling. Maps functional drivers of oncogenesis and metastasis, and develops novel cancer immunotherapy, cell therapy, and gene therapy approaches.", "tags": ["CRISPR", "cancer genomics", "immunotherapy", "gene therapy", "functional genomics"], "skills": ["CRISPR screens", "in vivo mouse models", "lentiviral library", "single-cell sequencing"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Caron Lab", "pi": "Etienne Caron", "department": "immunobiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/caron", "raw_description": "International leader in immunopeptidomics for global analysis of MHC-associated peptides using mass spectrometry. Initiated the Human Immunopeptidome Project. Research has potential to transform vaccine design, cancer immunotherapy, and neoantigen discovery.", "tags": ["immunopeptidomics", "mass spectrometry", "MHC", "neoantigen", "cancer immunotherapy", "vaccine"], "skills": ["mass spectrometry", "proteomics", "immunology", "bioinformatics"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Goodman Lab", "pi": "Andrew Goodman", "department": "microbial pathogenesis", "contact_email": "", "lab_url": "https://goodmanlab.yale.edu", "raw_description": "Uses microbial genetics, gnotobiotics, and mass spectrometry to understand how gut microbes interact with their host during health and disease. Also studies how the microbiome impacts the efficacy and toxicity of medical drugs.", "tags": ["microbiome", "gut bacteria", "microbial genetics", "gnotobiotics", "drug metabolism"], "skills": ["germ-free mouse models", "mass spectrometry", "microbial genetics", "metagenomics"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Hafler Lab", "pi": "David Hafler", "department": "neurology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/hafler", "raw_description": "Discovers the pathogenesis and treatment of multiple sclerosis. Identified circulating human autoreactive T cells, mechanisms of human regulatory T cell dysregulation, and genetic variants that alter immune responses in MS.", "tags": ["multiple sclerosis", "autoimmunity", "T cell", "neuroinflammation", "neuroimmunology", "GWAS"], "skills": ["flow cytometry", "patient samples", "GWAS", "single-cell RNA-seq"], "working_style": "mixed", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Goldman-Israelow Lab", "pi": "Benjamin Goldman-Israelow", "department": "internal medicine", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/goldman-israelow", "raw_description": "Focused on developing mucosal immune memory to emerging and endemic respiratory pathogens including SARS-CoV-2. Studies correlates of protection and transmission of pandemic-associated pathogens, and develops next-generation mucosal vaccines.", "tags": ["SARS-CoV-2", "mucosal immunity", "vaccine", "respiratory pathogens", "COVID-19"], "skills": ["mouse models", "viral assays", "flow cytometry", "patient samples"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Favuzzi Lab", "pi": "Emilia Favuzzi", "department": "neuroscience", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/favuzzi", "raw_description": "Studies immune and glial mechanisms underlying brain wiring and function. Discovered that specialized microglia differentially engage with specific synapse types. Investigates neuroimmune crosstalk in cortical circuit development.", "tags": ["microglia", "synapse", "neuroimmunology", "inhibitory circuits", "brain wiring", "neurodevelopment"], "skills": ["mouse models", "two-photon microscopy", "single-cell RNA-seq", "immunofluorescence"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Krishnaswamy Lab", "pi": "Smita Krishnaswamy", "department": "genetics", "contact_email": "", "lab_url": "https://krishnaswamylab.org", "raw_description": "Develops geometric deep learning and manifold learning methods for single-cell genomics, enabling analysis of high-dimensional biological data to understand cellular differentiation, disease, and biological trajectories.", "tags": ["machine learning", "single-cell", "genomics", "deep learning", "manifold learning", "data science"], "skills": ["Python", "PyTorch", "scRNA-seq", "deep learning"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Giraldez Lab", "pi": "Antonio Giraldez", "department": "genetics", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/giraldez", "raw_description": "Studies the role of microRNAs and RNA regulation during embryonic development. Uses zebrafish as a model system to understand gene expression programs and mRNA clearance driving cell fate decisions during the maternal-to-zygotic transition.", "tags": ["microRNA", "RNA regulation", "zebrafish", "embryonic development", "gene expression", "cell fate"], "skills": ["zebrafish genetics", "RNA-seq", "CRISPR", "live imaging"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Noonan Lab", "pi": "James Noonan", "department": "genetics", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/noonan", "raw_description": "Investigates the genomic and epigenomic basis of human brain evolution and neurodevelopmental disorders. Uses comparative genomics in human and non-human primate cells to identify human-specific regulatory elements.", "tags": ["human evolution", "brain development", "epigenomics", "comparative genomics", "neurodevelopment"], "skills": ["ATAC-seq", "ChIP-seq", "comparative genomics", "cell culture"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "De Camilli Lab", "pi": "Pietro De Camilli", "department": "neuroscience", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/decamilli", "raw_description": "Studies membrane dynamics and vesicle trafficking at the synapse. Focuses on endocytosis, phosphoinositide signaling, and synaptic vesicle recycling mechanisms essential for neurotransmission.", "tags": ["synapse", "endocytosis", "vesicle trafficking", "phosphoinositide", "neuroscience"], "skills": ["electron microscopy", "biochemistry", "cell culture", "mouse models"], "working_style": "wet", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Crawford Lab", "pi": "Jason Crawford", "department": "chemistry", "contact_email": "", "lab_url": "https://crawfordlab.yale.edu", "raw_description": "Studies the chemical ecology of the microbiome, discovering small molecules produced by gut bacteria that modulate host immunity, behavior, and pathogen competition. Integrates organic chemistry, microbiology, and chemical biology.", "tags": ["chemical biology", "microbiome", "natural products", "host-microbe", "small molecules", "immunology"], "skills": ["organic synthesis", "mass spectrometry", "microbiology", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Dietrich Lab", "pi": "Marcelo Dietrich", "department": "comparative medicine", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/dietrich", "raw_description": "Investigates the neuroendocrine mechanisms that control feeding behavior, energy balance, and motivation. Uses mouse genetics, live imaging, and circuit dissection to understand hypothalamic and limbic regulation of metabolism.", "tags": ["feeding behavior", "metabolism", "hypothalamus", "neural circuit", "energy balance", "neuroendocrine"], "skills": ["mouse models", "optogenetics", "fiber photometry", "in vivo imaging"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Breaker Lab", "pi": "Ronald Breaker", "department": "mb&b", "contact_email": "", "lab_url": "https://breakerlab.yale.edu", "raw_description": "Pioneered the study of riboswitches — RNA elements in bacterial mRNAs that control gene expression by binding small molecules. Continues to discover new classes of non-coding RNA and RNA-based regulatory mechanisms.", "tags": ["riboswitch", "non-coding RNA", "RNA biology", "gene regulation", "bacteria", "structural biology"], "skills": ["RNA biochemistry", "structural probing", "bioinformatics", "molecular biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Strobel Lab", "pi": "Scott Strobel", "department": "mb&b", "contact_email": "", "lab_url": "https://strobel.yale.edu", "raw_description": "Studies the chemical basis of RNA catalysis and the ribosome. Also leads expeditions to discover bioactive natural products from endophytic fungi in tropical rainforests, including potential anti-cancer and anti-infective compounds.", "tags": ["ribosome", "RNA catalysis", "natural products", "endophyte", "chemical biology", "structural biology"], "skills": ["RNA chemistry", "organic synthesis", "mass spectrometry", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Xiong Lab", "pi": "Yong Xiong", "department": "mb&b", "contact_email": "yong.xiong@yale.edu", "lab_url": "https://xionglab.yale.edu", "raw_description": "Uses X-ray crystallography and cryo-EM to determine high-resolution structures of proteins involved in HIV restriction, innate immunity, and DNA repair. Focuses on understanding host-pathogen interactions at atomic resolution.", "tags": ["structural biology", "cryo-EM", "X-ray crystallography", "HIV", "innate immunity", "DNA repair"], "skills": ["cryo-EM", "X-ray crystallography", "protein purification", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Bleichert Lab", "pi": "Franziska Bleichert", "department": "mb&b", "contact_email": "franziska.bleichert@yale.edu", "lab_url": "https://medicine.yale.edu/lab/bleichert", "raw_description": "Investigates the molecular mechanisms of DNA replication initiation, focusing on the structure and function of origin recognition complexes and replicative helicases using biochemistry and cryo-EM.", "tags": ["DNA replication", "structural biology", "cryo-EM", "replicative helicase", "origin recognition"], "skills": ["cryo-EM", "biochemistry", "protein purification", "molecular biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Baserga Lab", "pi": "Susan Baserga", "department": "mb&b", "contact_email": "susan.baserga@yale.edu", "lab_url": "https://medicine.yale.edu/lab/baserga", "raw_description": "Studies the biogenesis of ribosomes, specifically how ribosomal RNA is processed and assembled into functional ribosomal subunits. Uses yeast and human cell models to identify factors essential for ribosome production and cell growth.", "tags": ["ribosome biogenesis", "rRNA processing", "RNA biology", "ribosomopathies", "cell growth"], "skills": ["yeast genetics", "RNA biochemistry", "cryo-EM", "cell culture"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Ellman Lab", "pi": "Jonathan Ellman", "department": "chemistry", "contact_email": "", "lab_url": "https://ellman.chem.yale.edu", "raw_description": "Develops new synthetic methods in catalysis and chemical biology. Leverages C-H functionalization, asymmetric synthesis, and high-throughput chemistry to create bioactive small molecules and study biological systems.", "tags": ["organic synthesis", "catalysis", "chemical biology", "C-H functionalization", "drug discovery"], "skills": ["organic synthesis", "catalysis", "NMR", "high-throughput screening"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Miller Lab", "pi": "Scott Miller", "department": "chemistry", "contact_email": "", "lab_url": "https://millerlab.yale.edu", "raw_description": "Develops peptide-based asymmetric catalysts inspired by enzymes, enabling site-selective and stereoselective reactions on complex natural products. Works at the interface of organic synthesis, catalysis, and chemical biology.", "tags": ["asymmetric catalysis", "peptide catalysis", "organic synthesis", "natural products", "chemical biology"], "skills": ["organic synthesis", "peptide chemistry", "NMR", "HPLC"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Herzon Lab", "pi": "Seth Herzon", "department": "chemistry", "contact_email": "", "lab_url": "https://herzon.chem.yale.edu", "raw_description": "Designs and synthesizes complex natural products with anticancer and microbiome-modulating activities. Illuminates the molecular mechanisms of action of natural products through total synthesis and chemical biology tools.", "tags": ["total synthesis", "natural products", "anticancer", "microbiome", "chemical biology", "organic chemistry"], "skills": ["organic synthesis", "total synthesis", "mass spectrometry", "NMR"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Spiegel Lab", "pi": "David Spiegel", "department": "chemistry", "contact_email": "", "lab_url": "https://spiegellab.yale.edu", "raw_description": "Develops bifunctional small molecules that redirect the immune system to kill cancer cells, including Antibody-Recruiting Molecules (ARMs). Also studies glycobiology and designs probes to manipulate glycan biology in living systems.", "tags": ["cancer immunotherapy", "antibody recruiting", "glycobiology", "chemical biology", "drug discovery"], "skills": ["organic synthesis", "cell culture", "flow cytometry", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Newhouse Lab", "pi": "Timothy Newhouse", "department": "chemistry", "contact_email": "", "lab_url": "https://newhouselab.yale.edu", "raw_description": "Develops new strategies for the total synthesis of complex natural products, particularly terpenoids and alkaloids with biological activity. Integrates transition-metal catalysis and computational tools to design efficient synthetic routes.", "tags": ["total synthesis", "terpenoids", "alkaloids", "organic synthesis", "catalysis", "natural products"], "skills": ["organic synthesis", "NMR", "HPLC", "computational chemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Slavoff Lab", "pi": "Sarah Slavoff", "department": "chemistry", "contact_email": "", "lab_url": "https://slavofflab.yale.edu", "raw_description": "Discovers and characterizes novel microproteins encoded in non-canonical open reading frames across the human genome using mass spectrometry and chemical biology tools. Studies how these microproteins regulate cell biology and disease.", "tags": ["microproteins", "proteomics", "mass spectrometry", "non-canonical ORFs", "chemical biology", "translation"], "skills": ["mass spectrometry", "biochemistry", "cell culture", "chemical biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Malaker Lab", "pi": "Stacy Malaker", "department": "chemistry", "contact_email": "", "lab_url": "https://malakerlab.yale.edu", "raw_description": "Develops mass spectrometry-based tools to characterize glycoproteins, with a focus on mucins and their roles in cancer and immunity. Combines chemical biology and proteomics to map the glycoproteome in disease contexts.", "tags": ["glycoproteomics", "mass spectrometry", "mucins", "cancer", "proteomics", "chemical biology"], "skills": ["mass spectrometry", "glycoproteomics", "cell culture", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Bhattacharyya Lab", "pi": "Moitrayee Bhattacharyya", "department": "pharmacology", "contact_email": "", "lab_url": "https://medicine.yale.edu/profile/moitrayee-bhattacharyya", "raw_description": "Studies molecular mechanisms of kinase signaling in the context of learning, memory, and neuropathological conditions. Uses structural biology, single-molecule microscopy, and native mass spectrometry to study CaMKII regulation.", "tags": ["kinase signaling", "CaMKII", "learning", "memory", "structural biology", "single-molecule"], "skills": ["single-molecule microscopy", "cryo-EM", "native mass spectrometry", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Arnsten Lab", "pi": "Amy Arnsten", "department": "neuroscience", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/arnsten", "raw_description": "Studies molecular regulation of higher cortical circuits, particularly prefrontal cortex. Research revealed that newly evolved cortical circuits are uniquely regulated, conferring vulnerability in mental illness and age-related cognitive disorders like Alzheimer's disease. Led to new treatments for ADHD.", "tags": ["prefrontal cortex", "cognition", "ADHD", "Alzheimer's", "aging", "schizophrenia", "PTSD"], "skills": ["mouse models", "non-human primates", "electrophysiology", "neuroimaging"], "working_style": "mixed", "undergrad_friendly": "unlikely", "openings_status": "selective", "funding_level": "high", "metadata_estimated": true }, { "name": "Chang Lab (Vagus)", "pi": "Rui Chang", "department": "neuroscience", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/ruichang", "raw_description": "Studies how body sensory cues are monitored by the brain through the vagus nerve and how internal signals regulate whole body physiology. Uses optogenetics, chemogenetics, and single-cell profiling to reveal organ-to-brain circuits.", "tags": ["vagus nerve", "gut-brain axis", "organ-to-brain", "optogenetics", "autonomic nervous system"], "skills": ["optogenetics", "chemogenetics", "single-cell RNA-seq", "virus-based mapping"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Steve Chang Lab", "pi": "Steve W.C. Chang", "department": "psychology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/stevechang", "raw_description": "Studies neural circuit mechanisms of social cognition and social decision-making using naturalistic social interaction paradigms, electrophysiology, and state-of-the-art behavioral neuroscience technologies in primates.", "tags": ["social cognition", "decision-making", "prefrontal cortex", "amygdala", "neural circuits", "psychiatry"], "skills": ["electrophysiology", "primate behavior", "neural data analysis", "MATLAB"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Cardin Lab", "pi": "Jessica Cardin", "department": "neuroscience", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/cardin", "raw_description": "Studies the cellular and circuit mechanisms that regulate cortical dynamics during sensory processing and cognition, with a focus on the role of interneurons in generating oscillations and their disruption in autism and schizophrenia.", "tags": ["cortical circuits", "interneurons", "oscillations", "autism", "schizophrenia", "sensory processing"], "skills": ["in vivo electrophysiology", "two-photon imaging", "optogenetics", "mouse models"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Carlson Lab", "pi": "John Carlson", "department": "mcdb", "contact_email": "", "lab_url": "https://carlsonlab.yale.edu", "raw_description": "Studies the molecular and cellular basis of olfaction and taste in Drosophila. Discovered the first insect odor and taste receptors, elucidated logic of odor coding, and now studies chemoreception in disease-transmitting mosquitoes.", "tags": ["olfaction", "taste", "Drosophila", "mosquito", "chemosensory", "receptors", "neuroscience"], "skills": ["Drosophila genetics", "electrophysiology", "behavioral assays", "molecular biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Chandra Lab", "pi": "Sreeganga Chandra", "department": "neurology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/chandra", "raw_description": "Studies neuronal cell biology and synaptic dysfunction in neurodegenerative diseases, including Parkinson's disease and neuronal ceroid lipofuscinoses, with a focus on presynaptic proteins and lysosomal function.", "tags": ["Parkinson's disease", "synapse", "neurodegeneration", "lysosome", "presynaptic", "neurology"], "skills": ["mouse models", "electron microscopy", "biochemistry", "cell culture"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Bhattacharjee Lab (CS)", "pi": "Abhishek Bhattacharjee", "department": "computer science", "contact_email": "", "lab_url": "https://engineering.yale.edu/research-and-faculty/faculty-directory/abhishek-bhattacharjee", "raw_description": "Studies computer architectures and systems for platforms ranging from data center servers to brain-computer interfaces. Builds chips for brain-computer interfaces (HALO project) evaluated on epilepsy patients and non-human primates.", "tags": ["computer architecture", "brain-computer interface", "GPU", "systems software", "neuromorphic computing"], "skills": ["computer architecture", "VLSI", "systems programming", "C++"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Butterwick Lab", "pi": "Joel Butterwick", "department": "pharmacology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/butterwick", "raw_description": "Studies smell and taste receptors using single-particle cryo-electron microscopy to elucidate the elementary principles of chemosensory detection. Determined the first high-resolution structure of an olfactory receptor.", "tags": ["olfaction", "taste", "cryo-EM", "receptor structure", "ion channels", "pharmacology"], "skills": ["cryo-EM", "protein purification", "electrophysiology", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Bagriantsev Lab", "pi": "Slav Bagriantsev", "department": "cellular and molecular physiology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/bagriantsev", "raw_description": "Studies the biophysics of ion channels and sensory receptor cells, particularly mechanoreceptors and thermoreceptors. Examines potassium channels, TRP channels, and voltage-gated sodium channels in somatosensory neurons.", "tags": ["ion channels", "mechanoreception", "thermoreception", "biophysics", "sensory neurons", "TRP channels"], "skills": ["electrophysiology", "patch clamp", "Xenopus oocytes", "mouse models"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Brennand Lab", "pi": "Kristen Brennand", "department": "psychiatry", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/brennand", "raw_description": "Combines genomic engineering, neuroscience, and stem cells to identify mechanisms underlying brain disease. Uses patient iPSC-derived neurons to model psychiatric disorders including schizophrenia, bipolar disorder, and autism.", "tags": ["iPSC", "stem cells", "schizophrenia", "bipolar disorder", "psychiatric genetics", "neurodevelopment"], "skills": ["iPSC culture", "CRISPR", "single-cell RNA-seq", "neuronal differentiation"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Blumberg Lab", "pi": "Hilary Blumberg", "department": "psychiatry", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/blumberg", "raw_description": "Investigates the brain circuitry differences underlying mood disorders across the lifespan, with a focus on bipolar disorder and suicide prevention. Uses neuroimaging, genetics, and multimodal approaches to develop early detection methods.", "tags": ["bipolar disorder", "depression", "neuroimaging", "fMRI", "suicide", "adolescent psychiatry"], "skills": ["fMRI", "diffusion tensor imaging", "MATLAB", "R"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Blumenfeld Lab", "pi": "Hal Blumenfeld", "department": "neurology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/blumenfeld", "raw_description": "Studies the neural mechanisms of epilepsy, consciousness, and cognition using EEG, fMRI, and intracranial recordings. Directs the Yale Clinical Neuroscience Imaging Center and has authored a major neuroanatomy textbook.", "tags": ["epilepsy", "consciousness", "EEG", "fMRI", "neuroimaging", "cognition"], "skills": ["EEG", "fMRI", "intracranial recording", "human neuroscience"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Stearns Lab", "pi": "Stephen Stearns", "department": "eeb", "contact_email": "", "lab_url": "https://stearnslab.yale.edu", "raw_description": "Specializes in life history evolution, linking ecology and evolutionary biology. Studies trade-offs between reproduction and survival, evolutionary medicine, and how natural selection shapes aging and human health.", "tags": ["life history evolution", "evolutionary medicine", "aging", "natural selection", "ecology"], "skills": ["quantitative genetics", "field ecology", "mathematical modeling", "R"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Jetz Lab", "pi": "Walter Jetz", "department": "eeb", "contact_email": "walter.jetz@yale.edu", "lab_url": "https://jetzlab.yale.edu", "raw_description": "Focuses on macroecology, community ecology, biogeography, and global change biology. Directs the Yale Center for Biodiversity and Global Change. Develops remote sensing and machine learning tools for mapping global biodiversity.", "tags": ["macroecology", "biogeography", "biodiversity", "global change", "remote sensing", "conservation"], "skills": ["R", "Python", "GIS", "remote sensing", "species distribution modeling"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Vasseur Lab", "pi": "David Vasseur", "department": "eeb", "contact_email": "david.vasseur@yale.edu", "lab_url": "https://vasseurlab.yale.edu", "raw_description": "Studies theoretical ecology with a focus on how environmental variability affects population, community, and ecosystem processes. Investigates biodiversity-ecosystem function relationships and spatial population synchrony.", "tags": ["theoretical ecology", "biodiversity", "population ecology", "environmental variability", "ecosystem function"], "skills": ["mathematical modeling", "R", "statistical analysis", "field ecology"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Post Lab", "pi": "David Post", "department": "eeb", "contact_email": "", "lab_url": "https://postlab.yale.edu", "raw_description": "Aquatic ecologist testing questions about food web structure and dynamics and the influence of environmental change on aquatic ecosystems. Develops and applies stable isotope techniques to address questions across ecology and evolutionary biology.", "tags": ["aquatic ecology", "food web", "stable isotopes", "environmental change", "trophic ecology"], "skills": ["stable isotope analysis", "field ecology", "R", "statistical modeling"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Prum Lab", "pi": "Richard Prum", "department": "eeb", "contact_email": "", "lab_url": "https://prumlab.yale.edu", "raw_description": "Studies the evolution of bird feathers, color, and signal. Investigates the physics of structural color in biological nanostructures, evolution of sexual ornaments, and avian phylogenetics. Also studies the evolutionary origins of beauty.", "tags": ["bird evolution", "structural color", "sexual selection", "phylogenetics", "feathers", "biophotonics"], "skills": ["electron microscopy", "spectrophotometry", "phylogenetic methods", "field work"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Turner Lab", "pi": "Paul Turner", "department": "eeb", "contact_email": "", "lab_url": "https://turnerlab.yale.edu", "raw_description": "Studies the ecology and evolution of viruses, including phage-bacteria coevolution, viral host range evolution, and the use of bacteriophages as therapeutics against drug-resistant bacterial infections.", "tags": ["virology", "phage evolution", "phage therapy", "host-pathogen", "coevolution", "antimicrobial resistance"], "skills": ["phage biology", "bacterial genetics", "evolutionary experiments", "molecular biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Donoghue Lab", "pi": "Michael Donoghue", "department": "eeb", "contact_email": "", "lab_url": "https://donoghuelab.yale.edu", "raw_description": "Studies plant phylogenetics and the evolution of plant diversity, with an emphasis on understanding why some groups of organisms diversify and others do not. Research spans from deep-time molecular phylogenetics to biogeography.", "tags": ["plant evolution", "phylogenetics", "biogeography", "diversification", "systematics"], "skills": ["phylogenetic methods", "bioinformatics", "R", "field work"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Near Lab", "pi": "Thomas Near", "department": "eeb", "contact_email": "", "lab_url": "https://nearlab.org", "raw_description": "Studies the evolutionary diversification of fishes using phylogenomics, comparative genomics, and paleontology. Focuses on Antarctic notothenioid fishes as models for understanding rapid evolution and adaptation to extreme environments.", "tags": ["fish evolution", "phylogenomics", "Antarctic", "adaptation", "comparative genomics", "paleontology"], "skills": ["phylogenomics", "genome sequencing", "comparative anatomy", "R"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Edwards Lab", "pi": "Erika Edwards", "department": "eeb", "contact_email": "", "lab_url": "https://edwardslab.org", "raw_description": "Studies plant evolutionary ecology and how plants have diversified across different climates. Focuses on the evolution of C4 photosynthesis, drought adaptation, and how evolutionary history shapes plant community assembly.", "tags": ["plant evolution", "C4 photosynthesis", "drought adaptation", "climate", "phylogenetics", "ecology"], "skills": ["phylogenetics", "physiological measurements", "R", "field work"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Caccone Lab", "pi": "Adalgisa Caccone", "department": "eeb", "contact_email": "", "lab_url": "https://caccone.yale.edu", "raw_description": "Studies evolutionary genetics and conservation genomics, with a focus on island biogeography. Uses population genomics and phylogeography to study Galapagos tortoises, African lions, and other organisms for conservation management.", "tags": ["conservation genetics", "population genomics", "Galapagos", "island biogeography", "phylogeography"], "skills": ["RAD-seq", "whole-genome sequencing", "population genetics", "R"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Grubaugh Lab", "pi": "Nathan Grubaugh", "department": "eeb", "contact_email": "", "lab_url": "https://grubaughlab.com", "raw_description": "Studies the evolution and epidemiology of mosquito-transmitted viruses including Zika, dengue, West Nile, and SARS-CoV-2 using genomic epidemiology, phylodynamics, and experimental evolution.", "tags": ["genomic epidemiology", "arbovirus", "Zika", "dengue", "West Nile", "COVID-19", "phylodynamics"], "skills": ["whole-genome sequencing", "phylogenetics", "bioinformatics", "virology"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Staver Lab", "pi": "Carla Staver", "department": "eeb", "contact_email": "", "lab_url": "https://staverlab.yale.edu", "raw_description": "Studies savanna and grassland ecology, fire ecology, and tree-grass coexistence in tropical biomes. Uses field data, remote sensing, and mathematical models to understand vegetation dynamics under global change.", "tags": ["savanna ecology", "fire ecology", "tree-grass coexistence", "remote sensing", "global change", "Africa"], "skills": ["R", "remote sensing", "mathematical modeling", "field ecology"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Munoz Lab", "pi": "Martha Munoz", "department": "eeb", "contact_email": "", "lab_url": "https://marthamunoz.com", "raw_description": "Studies how organisms evolve in response to environmental change, focusing on thermal adaptation, the role of behavior in evolution, and how phenotypic plasticity shapes evolutionary trajectories in Anolis lizards.", "tags": ["thermal adaptation", "behavioral evolution", "phenotypic plasticity", "Anolis", "climate change", "evo-devo"], "skills": ["field work", "thermal physiology", "genomics", "R"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Dunn Lab", "pi": "Casey Dunn", "department": "eeb", "contact_email": "", "lab_url": "https://dunnlab.org", "raw_description": "Studies animal evolution, phylogenomics, and the comparative biology of animal body plans. Develops computational methods for phylogenomics and has discovered new aspects of siphonophore colony biology.", "tags": ["animal evolution", "phylogenomics", "siphonophores", "marine biology", "comparative genomics", "bioinformatics"], "skills": ["phylogenomics", "Python", "R", "bioinformatics"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Irish Lab", "pi": "Vivian Irish", "department": "mcdb", "contact_email": "", "lab_url": "https://irishlab.yale.edu", "raw_description": "Studies the molecular and genetic mechanisms that control flower development and plant morphogenesis. Uses Arabidopsis thaliana as a model to understand how transcription factors and signaling pathways specify floral organ identity.", "tags": ["plant development", "flower development", "Arabidopsis", "transcription factors", "morphogenesis"], "skills": ["Arabidopsis genetics", "confocal microscopy", "ChIP-seq", "molecular biology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Toomre Lab", "pi": "Derek Toomre", "department": "cell biology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/toomre", "raw_description": "Develops advanced live-cell imaging technologies, including TIRF and light-sheet microscopy, to study intracellular membrane trafficking, exocytosis, and organelle dynamics with nanometer precision.", "tags": ["live-cell imaging", "TIRF microscopy", "membrane trafficking", "exocytosis", "organelle", "cell biology"], "skills": ["TIRF microscopy", "light-sheet microscopy", "Python", "image analysis"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Gupta Lab", "pi": "Kallol Gupta", "department": "cell biology", "contact_email": "kallol.gupta@yale.edu", "lab_url": "https://medicine.yale.edu/lab/gupta", "raw_description": "Uses cryo-EM and structural biology to study membrane protein complexes, including GPCRs, ion channels, and lipid-protein interactions, to understand their mechanisms and guide drug discovery.", "tags": ["cryo-EM", "GPCR", "ion channels", "membrane proteins", "structural biology", "drug discovery"], "skills": ["cryo-EM", "protein purification", "lipid nanodiscs", "structural analysis"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Townsend Lab", "pi": "Jeffrey Townsend", "department": "biostatistics", "contact_email": "", "lab_url": "https://townsend.yale.edu", "raw_description": "Develops statistical and computational methods for phylogenomics, evolutionary biology, and cancer genomics. Uses comparative genomic approaches to study cancer evolution, mutation rates, and virulence evolution in pathogens.", "tags": ["phylogenomics", "cancer evolution", "biostatistics", "evolutionary biology", "computational biology"], "skills": ["Python", "R", "phylogenetics", "bioinformatics"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Lindenbach Lab", "pi": "Brett Lindenbach", "department": "microbial pathogenesis", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/lindenbach", "raw_description": "Studies the molecular biology of positive-strand RNA viruses, particularly hepatitis C virus (HCV) and flaviviruses. Focuses on viral replication mechanisms, virus-host interactions, and antiviral drug development.", "tags": ["virology", "hepatitis C", "flavivirus", "RNA virus", "antiviral", "virus replication"], "skills": ["cell culture", "viral assays", "molecular biology", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Wagner Lab", "pi": "Gunter Wagner", "department": "eeb", "contact_email": "", "lab_url": "https://campuspress.yale.edu/wagner", "raw_description": "Studies evolutionary developmental biology and the evolution of novelty. Focuses on the origin of new cell types, transcription factor networks, and the uterus as a model for evolutionary innovations in mammals.", "tags": ["evo-devo", "evolutionary novelty", "cell type evolution", "uterus", "transcription factors", "mammalian evolution"], "skills": ["comparative genomics", "single-cell RNA-seq", "bioinformatics", "mouse models"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "high", "metadata_estimated": true }, { "name": "Powell Lab", "pi": "Jeffrey Powell", "department": "eeb", "contact_email": "", "lab_url": "https://www.yale.edu/powell", "raw_description": "Studies population genetics and evolutionary biology of insects, with a focus on Aedes aegypti and Drosophila. Has worked on sterile insect technique and Wolbachia-based methods for dengue vector control.", "tags": ["population genetics", "mosquito", "Aedes aegypti", "Drosophila", "vector control", "evolutionary genetics"], "skills": ["population genetics", "molecular biology", "field ecology", "sequencing"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Brodersen Lab", "pi": "Craig Brodersen", "department": "eeb", "contact_email": "", "lab_url": "https://campuspress.yale.edu/brodersenlab", "raw_description": "Studies plant hydraulics and vascular physiology, including how water moves through the xylem and how plants tolerate drought. Uses synchrotron X-ray imaging and micro-CT to visualize plant vascular anatomy in 3D.", "tags": ["plant physiology", "hydraulics", "drought tolerance", "xylem", "micro-CT", "climate change"], "skills": ["micro-CT", "synchrotron imaging", "plant physiology", "R"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Skelly Lab", "pi": "David Skelly", "department": "eeb", "contact_email": "", "lab_url": "https://environment.yale.edu/profile/skelly", "raw_description": "Studies ecology and evolutionary biology of amphibians in human-altered landscapes. Research spans urban ecology, rapid adaptation to pollution and climate, and how local adaptation shapes population responses to environmental change.", "tags": ["amphibian ecology", "urban ecology", "rapid adaptation", "climate change", "population biology"], "skills": ["field ecology", "population genetics", "R", "mark-recapture"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Schmitz Lab", "pi": "Oswald Schmitz", "department": "eeb", "contact_email": "", "lab_url": "https://schmitz.environment.yale.edu", "raw_description": "Studies ecosystem ecology with a focus on predator-prey interactions and trophic cascades in terrestrial food webs. Examines how top-down and bottom-up forces shape ecosystem processes including nutrient cycling and carbon storage.", "tags": ["ecosystem ecology", "trophic cascade", "predator-prey", "carbon cycle", "food web", "grassland"], "skills": ["field experiments", "stable isotopes", "R", "ecosystem modeling"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Tucci Lab", "pi": "Serena Tucci", "department": "eeb", "contact_email": "", "lab_url": "https://campuspress.yale.edu/stucci", "raw_description": "Studies human evolutionary genetics and ancient DNA, with a focus on Neanderthal and Denisovan introgression in modern humans and the genetic basis of human adaptation to diverse environments.", "tags": ["human evolution", "ancient DNA", "Neanderthal", "population genetics", "archaic introgression"], "skills": ["ancient DNA", "whole-genome sequencing", "bioinformatics", "population genetics"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Decker Lab", "pi": "Mary Beth Decker", "department": "eeb", "contact_email": "", "lab_url": "https://deckerlab.yale.edu", "raw_description": "Studies marine ecology, with a focus on jellyfish bloom dynamics and their role in pelagic food webs. Investigates how environmental change including hypoxia and warming drives jellyfish population fluctuations.", "tags": ["marine ecology", "jellyfish", "food web", "hypoxia", "pelagic ecology", "climate change"], "skills": ["field ecology", "stable isotopes", "R", "ocean sampling"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Addy Lab", "pi": "Nii Addy", "department": "psychiatry", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/addy", "raw_description": "Investigates cholinergic, dopaminergic, and L-type calcium channel mechanisms mediating substance use and mood disorders. Also studies the ability of tobacco product flavor additives to alter nicotine use behavior and addiction.", "tags": ["addiction", "dopamine", "cholinergic", "substance use", "nicotine", "mood disorders"], "skills": ["electrochemistry", "in vivo microdialysis", "rodent behavior", "pharmacology"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Allsop Lab", "pi": "AZA Allsop", "department": "psychiatry", "contact_email": "", "lab_url": "", "raw_description": "Conducts research at the intersection of social cognition, music, mindfulness, and psychedelics. Studies how these tools provide a better understanding of how social groups function and offer insights into treating mental suffering.", "tags": ["psychedelics", "social cognition", "music", "mindfulness", "psychiatry", "mental health"], "skills": ["fMRI", "behavioral experiments", "EEG", "qualitative methods"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Bordey Lab", "pi": "Angelique Bordey", "department": "neurosurgery", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/bordey", "raw_description": "Studies the molecular mechanisms underlying brain malformations associated with mTOR pathway hyperactivation, including tuberous sclerosis and focal cortical dysplasia, which cause epilepsy and autism. Develops targeted therapies.", "tags": ["mTOR", "tuberous sclerosis", "epilepsy", "autism", "cortical malformation", "stem cells"], "skills": ["mouse models", "electrophysiology", "molecular biology", "confocal microscopy"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Biederer Lab", "pi": "Thomas Biederer", "department": "neurology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/biederer", "raw_description": "Studies the biology of synapses with goals of defining how synapses develop, understanding their roles in cognition, and investigating their disruption in brain disorders including schizophrenia, Parkinson's disease, and drug abuse.", "tags": ["synapse formation", "trans-synaptic", "cognition", "schizophrenia", "Parkinson's", "neurodevelopment"], "skills": ["mouse models", "confocal microscopy", "electrophysiology", "biochemistry"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Cafferty Lab", "pi": "William Cafferty", "department": "neurology", "contact_email": "", "lab_url": "https://medicine.yale.edu/lab/cafferty", "raw_description": "Studies neural plasticity and regeneration after spinal cord injury and demyelinating disease. Focuses on the molecular mechanisms that inhibit axon growth in the adult CNS and strategies to promote functional recovery.", "tags": ["spinal cord injury", "axon regeneration", "neural plasticity", "demyelination", "pain", "CNS repair"], "skills": ["mouse models", "behavioral testing", "molecular biology", "confocal microscopy"], "working_style": "wet", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Dal Bello Lab", "pi": "Martina Dal Bello", "department": "eeb", "contact_email": "", "lab_url": "https://martinadalbello.com", "raw_description": "Studies microbial ecology and the dynamics of microbial communities using quantitative approaches. Combines theory and experiments to understand community assembly, species interactions, and ecological resilience in microbiomes.", "tags": ["microbial ecology", "community assembly", "species interactions", "microbiome", "ecological theory"], "skills": ["microbiology", "flow cytometry", "mathematical modeling", "Python"], "working_style": "mixed", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true }, { "name": "Eaton Lab", "pi": "Deren Eaton", "department": "eeb", "contact_email": "", "lab_url": "https://www.dereneaton.com", "raw_description": "Studies plant speciation and the genomics of hybridization and introgression. Develops RAD-seq and phylogenomic software tools for population and phylogenetic inference in rapidly radiating plant groups.", "tags": ["speciation", "hybridization", "phylogenomics", "RAD-seq", "plant evolution", "bioinformatics"], "skills": ["RAD-seq", "Python", "phylogenetics", "bioinformatics"], "working_style": "dry", "undergrad_friendly": "yes", "openings_status": "likely_open", "funding_level": "medium", "metadata_estimated": true } ]